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IISER Kolkata achieves breakthrough in Cancer Drug Delivery

Targeted delivery of anticancer drugs exclusively to cancer cells and controlled release of the drugs in a sustained manner inside cancer cells has been achieved by a group of researchers from the Indian Institute of Science Education and Research (IISER) Kolkata. 
●    Porous carbon nanospheres about 150 nm in diameter and packed with drugs inside the pores has been designed in such a way that they cannot get inside normal cells and kill them. 
●    The results were published in the journal Carbon.
●    A team led by Dr. Sayan Bhattacharyya from the Department of Chemical Sciences, IISER Kolkata, used the commonly available lemon grass to synthesise the porous carbon nanospheres, which act as drug carriers. 
●    The anticancer drug doxorubicin is covalently bound both inside the 3.6-3.8 nm diameter pores and also on the surface of the nanospheres. 
●    To make the targeted delivery nearly fail-proof, the researchers attached folic acid to the nanospheres. 


 

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